Arthramid Vet 2.5% PAAG. The Future of Arthritis Treatment

Arthramid Hydrogel
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Case Selection & Management
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Proven Science. Proven Results

Arthramid Vet is an unique & patented hydrogel offering an innovative, safe solution for Veterinarians.

Arthramid® Vet is used to treat non-infectious causes of joint lameness in animals, including both early and late stage of Osteoarthritis (OA) and Degenerative Joint Disease (DJD). 

Lameness is the number one reason for vet call-outs and is often difficult to manage, especially in the longer term. This can lead to frequent re-treatments and, increased supplement and drug intake.  Arthramid® Vet treats the underlying causes of joint lameness in animals, including both early and late stages of osteoarthritis (OA). 

Overview

  • The new generation joint treatment
  • 2.5% cross-linked PAAG hydrogel
  • Long lasting- non absorbable
  • 82.5% successful resolution of joint lameness
  • Integrates into the joint tissue providing shock absorption to the joint
  • Safe, biocompatible, non toxic and neuro innocuous

 

listen to our PODCASTS

Listen to our series of Podcasts produced to help veterinarians and owners understand the science, research and benefits of this innovative product.

Episode 5

Episode 5: We talk to Australian legend Dr Kim McKellar, Equine Veterinarian, about his experiences of Arthramid Vet from over 50 years in clinical practice; "I wish I had this product 30 years ago".

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Episode 4

Episode 4: We meet expert and specialist surgeon Dr Aziz Tnibar, one of the original researcher's behind the use of 2.5% PAAG in the treatment of lameness and osteoarthritis in animals.

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Episode 3

Episode 3: We hear from expert veterinarian Dr Marc Koene, German Olympic Team Vet, FEI Advisor and Owner at Leusche Equine Clinic about his opinion and experiences with Arthramid Vet 

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Episode 2

Episode 2: We discuss how to use Arthramid Vet in the management of joint lameness and osteoarthritis in horses.

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Episode 1

Episode 1: An introduction to Arthramid Vet, an exciting new treatment for joint lameness and osteoarthritis in animals.

Our Philosophy

Every detail is taken care of

“Our philosophy of innovation remains at the centre of everything we do. Our core mission is to improve the health, performance, and wellbeing of equine patients through technological innovation, intensive R & D and global partner alliances in the veterinary industry leading to better patient outcomes and client enjoyment of the animals we love.”

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Innovative Medical Solutions

Arthramid Vet White Paper

Get your copy of our 24 page white paper covering Treatment of Joint Lameness, Pathophysiology, Manufacturing, Mechanism of Action, Clinical Safety and Putting it into Practice.

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Read About Case Selection

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Understanding the complexity of disease processes associated with joint pain remains a constant dilemma in clinical practice and as with any disease process, an accurate diagnosis is essential.

Arthritis describes inflammation of a joint and can occur after single or repetitive episodes of trauma. The term incorporates synovitis, capsulitis, sprain, intra-articular fractures, meniscal tears, and osteoarthritis(OA). Sub-chondral bone injury also plays a role.

These pathological conditions are ‘a group of overlapping distinct diseases which may have different aetiologies, but with similar biologic, morphologic, and clinical outcomes.

Although conventional concepts of OA emphasise the direct and predominant involvement of cartilage and bone in OA development, it is increasingly recognised that the synovium also contributes to the central pathophysiological event of cartilage matrix depletion.

Cases suitable for treatment with Arthramid®Vet are those in which lameness is localised to the joint by clinical examination, intra-articular analgesia, radiography, ultrasound, MRI, CT and/or Scintigraphy. Conditions that respond to treatment with Arthramid®Vet include acute and chronic synovitis, capsulitis, meniscal tears, OA, and subchondral bone cysts. It is essential that anamnesis of data of ongoing infection, concomitant medication, surgery or potential fracture is reviewed prior to injection to prevent possible infections or use of the product for conditions other than for which it is indicated.

Read About Case Management

Read More on Case Management Protocols

Animals should be rested for 48 hours immediately after treatment. After this time the animal can return to exercise compared to its level of comfort.

Clinical studies show that tissue integration and subsequent augmentation of the joint capsule takes between 2 and 4 weeks to occur, although a response to treatment can be seen earlier than that in some cases.

Animals typically show a gradual reduction in lameness during the first week after treatment and a concurrent reduction in reaction to passive flexion. This continues to improve over the ensuing 2 to 3 weeks. By 4 weeks no further improvement is expected. Re-examination at 4 weeks is therefore indicated to either administer a second dose – in those that have only partially responded- or to reassess accuracy of the diagnosis.

It is important for owners to understand the time lag for a treatment effect to be seen as this contrasts with conventional therapies. In this respect and due to its long lasting effect it may also be prudent to consider treating the animal during periods of reduced exercise demands or early on in the animals training programme.

Read About Mode Of Action

Not All Hydrogels Are The Same

PAAG products, although often considered equal, have clear differences in composition, manufacturing and injection techniques as well as their ability to interact with surrounding tissues. Characteristics that determine the safety and effectiveness of each hydrogel.

Upon injection into joints, the Arthramid® Vet, a uniquely cross-linked 2.5% polyacrylamide hydrogel, adheres to the synovial lining through its ability to exchange water molecules. The ensuing influx of mononuclear cells reduces exposure of synoviocytes to pro-inflammatory cytokines in the inflamed or diseased joint. The gel becomes progressively integrated into the synovial lining and its immediate surrounding tissue of the inner joint capsule by a combination of cell migration and vessel ingrowth forming a thick, cushion-like membrane, over 14 to 28 days, consisting of vessel integrated gel covered by a new and hypercellular synovial cell lining.

Arthramid®Vet, therefore, has an augmentation effect on the joint capsule and synovium, increasing elasticity and tensile strength and improving its capacity to transfer load. This augmentation and cushioning causes a subsequent reduction in mechanoreceptor and nociceptor activation in the capsule itself. In turn, this further reduces synovitis and its successively deleterious effects as a result.

Unlike other hydrogels, Arthramid®Vet becomes fully integrated into the surrounding tissue (rather than encapsulated) and is therefore long-lasting. Arthramid®Vet does not elicit a foreign body reaction or harbour infection.

Download User Guide

Arthramid Vet User Guide
Download User Guide : Arthramid Vet User Guide
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testimonials

Dr Kim Mckellar

I have been using Arthramid Vet for over 4 years treating TB’s, SB’s and equestrian horses. It’s simply the best treatment we have for OA”(read more) 

Dr Marc Koene

“I was one of the first vets to use Arthramid worldwide and the results are quite astonishing” (read more)

Dr Stuart Vallance

“I have learnt how to maximise its benefit in my caseload of predominantly Thoroughbred racehorses”   (read more)

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32 Hill Road, Cambridge, NZ Phone +64 (09) 8013 253 sales@imsvet.com

Arthramid Vet New Zealand

Registered in New Zealand to: Innovative Medical Solutions Limited NZBN: 9429041325544, 32 Hill Road, Cambridge 3494, New Zealand. Registered pursuant to the ACVM Act 1997 Number A11596. See www.foodsafety.govt.nz  for registration conditions.

32 Hill Road, Cambridge
PO Box 1083, Cambridge 3450
Phone +64 (09) 8013 253
sales@imsvet.com